Barbara Borroni Selected Research

Frontotemporal Dementia (Semantic Dementia)

8/2022	Anomia is present pre-symptomatically in frontotemporal dementia due to MAPT mutations.
1/2022	Conceptual framework for the definition of preclinical and prodromal frontotemporal dementia.
1/2022	A data-driven disease progression model of fluid biomarkers in genetic frontotemporal dementia.
1/2022	Development of a sensitive trial-ready poly(GP) CSF biomarker assay for C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis.
1/2022	Structural brain splitting is a hallmark of Granulin-related frontotemporal dementia.
12/2021	Dissemination in time and space in presymptomatic granulin mutation carriers: a GENFI spatial chronnectome study.
11/2021	A panel of CSF proteins separates genetic frontotemporal dementia from presymptomatic mutation carriers: a GENFI study.
10/2021	GluA3 autoantibodies induce alterations in dendritic spine and behavior in mice.
1/2021	Disease-related cortical thinning in presymptomatic granulin mutation carriers.
1/2021	NMDA and AMPA Receptor Autoantibodies in Brain Disorders: From Molecular Mechanisms to Clinical Features.

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Barbara Borroni Research Topics

Disease

65	Frontotemporal Dementia (Semantic Dementia) 08/2022 - 09/2005
60	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 01/2002
34	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 01/2022 - 08/2006
26	Dementia (Dementias) 01/2022 - 01/2002
21	Cognitive Dysfunction 01/2022 - 01/2002
16	Parkinson Disease (Parkinson's Disease) 11/2021 - 11/2009
14	Atrophy 01/2022 - 02/2011
13	Disease Progression 01/2022 - 06/2003
10	Neurodegenerative Diseases (Neurodegenerative Disease) 04/2022 - 01/2010
8	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2022 - 05/2014
7	Primary Progressive Aphasia 01/2021 - 01/2012
6	Ataxia (Dyssynergia) 01/2021 - 10/2015
5	Parkinsonian Disorders (Parkinsonism) 11/2021 - 09/2005
4	Type C Niemann-Pick Disease (Niemann Pick Disease, Type C) 09/2019 - 03/2015
4	Corticobasal Degeneration 11/2015 - 01/2010
4	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 11/2015 - 01/2010
3	Synucleinopathies 11/2021 - 07/2011
3	Tauopathies 11/2021 - 11/2012
3	Epilepsy (Aura) 10/2021 - 04/2012
3	Brain Diseases (Brain Disorder) 01/2021 - 11/2017
3	Proteostasis Deficiencies 01/2021 - 01/2019
3	Neurobehavioral Manifestations 01/2021 - 07/2004
3	Multiple System Atrophy 01/2020 - 08/2007
3	Amyloidosis 12/2019 - 12/2016
3	Migraine Disorders (Migraine) 03/2009 - 09/2005
2	Gliosis 01/2022 - 01/2020
2	Cerebrovascular Disorders (Cerebrovascular Occlusion) 12/2021 - 02/2012
2	Autoimmune Diseases of the Nervous System 10/2021 - 01/2021
2	Orthostatic Hypotension (Postural Hypotension) 01/2021 - 11/2019
2	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 01/2019 - 10/2017
2	Memory Disorders (Memory Loss) 01/2018 - 08/2006
2	Cerebellar Ataxia (Dysmetria) 03/2017 - 01/2017
2	Sarcoma (Soft Tissue Sarcoma) 01/2015 - 09/2011
2	Inflammation (Inflammations) 05/2014 - 07/2013
2	Stroke (Strokes) 01/2014 - 07/2004
2	Sporadic Creutzfeldt-Jakob Disease 11/2013 - 08/2011
2	Hypercholesterolemia 12/2006 - 06/2003
2	Psychotic Disorders (Schizoaffective Disorder) 12/2006 - 11/2004
2	Migraine with Aura (Familial Hemiplegic Migraine) 11/2006 - 09/2005
1	Brain Injuries (Brain Injury) 08/2022
1	Amyloid Plaque 04/2022
1	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 12/2021
1	Movement Disorders (Movement Disorder) 11/2021
1	Encephalitis (Encephalitis, Rasmussen) 10/2021

Drug/Important Bio-Agent (IBA)

43	Biomarkers (Surrogate Marker)IBA 08/2022 - 01/2002
24	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2002
19	ProgranulinsIBA 08/2022 - 07/2008
19	Amyloid (Amyloid Fibrils)IBA 04/2022 - 01/2002
18	GranulinsIBA 01/2022 - 10/2012
14	Biological ProductsIBA 01/2022 - 06/2002
13	Apolipoproteins E (ApoE)IBA 01/2022 - 06/2002
8	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 08/2022 - 01/2010
8	salicylhydroxamic acid (SHAM)IBA 05/2021 - 10/2015
7	Cholinergic Agents (Cholinergics)IBA 01/2022 - 01/2012
6	Cholinesterase Inhibitors (Anticholinesterases)IBA 12/2009 - 06/2003
5	Pharmaceutical PreparationsIBA 01/2022 - 12/2016
4	SynucleinsIBA 11/2021 - 07/2011
3	Glial Fibrillary Acidic ProteinIBA 01/2022 - 01/2020
3	DNA-Binding Proteins (DNA Binding Protein)IBA 01/2020 - 01/2015
3	Glucose (Dextrose)FDA LinkGeneric 01/2018 - 11/2005
3	Peptides (Polypeptides)IBA 01/2018 - 11/2010
3	Serotonin (5 Hydroxytryptamine)IBA 01/2015 - 09/2005
3	ApolipoproteinsIBA 01/2012 - 08/2006
3	CholesterolIBA 12/2006 - 06/2003
3	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 06/2005 - 02/2002
2	neuronal pentraxinIBA 01/2022 - 01/2020
2	Neurotransmitter Agents (Neurotransmitter)IBA 01/2022 - 01/2019
2	ClusterinIBA 11/2021 - 01/2020
2	AutoantibodiesIBA 10/2021 - 01/2021
2	AMPA Receptors (AMPA Receptor)IBA 10/2021 - 01/2021
2	N-Methylaspartate (NMDA)IBA 01/2021 - 11/2010
2	AntibodiesIBA 01/2021 - 01/2020
2	hydroxide ionIBA 01/2021 - 11/2019
2	CopperIBA 01/2021 - 01/2020
2	IronIBA 01/2020 - 01/2016
2	Transferrin (beta 2 Transferrin)IBA 01/2020 - 11/2013
2	Ceruloplasmin (Ferroxidase)IBA 01/2020 - 11/2013
2	Docosahexaenoic AcidsIBA 01/2019 - 10/2017
2	Insulin (Novolin)FDA Link 01/2018 - 01/2017
2	Phosphotransferases (Kinase)IBA 01/2018 - 01/2017
2	DNA (Deoxyribonucleic Acid)IBA 01/2017 - 09/2011
2	CytokinesIBA 05/2014 - 06/2011
2	Interleukin-18 (Interleukin 18)IBA 05/2014 - 06/2011
2	Messenger RNA (mRNA)IBA 05/2014 - 07/2013
2	Presenilin-1IBA 04/2012 - 01/2011
2	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2012 - 01/2009
2	UbiquitinIBA 09/2011 - 01/2010
2	technetium Tc 99m bicisate (Neurolite)FDA Link 08/2011 - 11/2005
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2010 - 01/2006
2	EsterasesIBA 01/2010 - 09/2006
2	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2010 - 09/2006
2	Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA 12/2006 - 11/2004
2	Donepezil (Aricept)FDA LinkGeneric 09/2004 - 06/2002
1	SuspensionsIBA 11/2021
1	Immunoglobulin G (IgG)IBA 10/2021

Therapy/Procedure

18	Transcranial Direct Current Stimulation 01/2022 - 01/2014
12	Therapeutics 01/2021 - 06/2003
11	Transcranial Magnetic Stimulation 10/2021 - 01/2016
3	Activities of Daily Living (ADL) 01/2020 - 11/2007
2	Language Therapy (Language Training) 01/2021 - 01/2014